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Are ‘N bands’ selective staining of specific heterochromatin?

Abstract

BY in situ DNA–RNA-hybridisation and the association patterns in meiotic and mitotic chromosomes, the nucleolus organiser regions (NOR) have been localised on specific chromosomal segments of some mammalian species1–4. Matsui and Sasaki5 described a staining technique (‘N bands’) which was assumed to stain the NOR of mammalian chromosomes with high specificity.

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References

  1. Henderson, A. S., Warburton, P., and Atwood, K. C., Proc. natn. Acad. Sci., U.S.A., 69, 3394–3398 (1972).

    Article  ADS  CAS  Google Scholar 

  2. Bross, K., and Krone, W., Humangenetik, 14, 137–141 (1972).

    Article  CAS  Google Scholar 

  3. Comings, D. E., Expl Cell Res., 67, 441–460 (1971).

    Article  CAS  Google Scholar 

  4. Ohno, S., Trujillo, J. M., Kaplan, W. D., and Kinoshita, R., Lancet, ii, 123–126 (1961).

    Article  Google Scholar 

  5. Matsui, S.-J., and Sasaki, M., Nature, 246, 148–150 (1973).

    Article  ADS  CAS  Google Scholar 

  6. Hsu, T. C., Brinkley, B. R., and Arrighi, F. E., Chromosoma, 23, 137–153 (1967).

    Article  CAS  Google Scholar 

  7. Ohnuki, Y., Olson, R. S., and Rounds, D. E., Jap. J. Genet., 47, 133 (1972).

    Article  Google Scholar 

  8. Hsu, T. C., and Arrighi, F., Chromosoma, 34, 243–253 (1971).

    CAS  PubMed  Google Scholar 

  9. Paris Conf. (1971). Standardization Human Cytogenet., Birth Defects (original article Series), VIII, 7 (The National Foundation, New York, 1972).

  10. Vogel, W., Faust, J., Schmid, M., and Siebers, J.-W., Humangenetik, 21, 227–236 (1974).

    CAS  PubMed  Google Scholar 

  11. Levan, A., Hsu, T. C., and Stich, H. F., Hereditas, 48, 677–687 (1962).

    Google Scholar 

  12. Hsu, T. C., Cooper, J. E., Mace, M. L., jun., and Brinkley, B. R., Chromosoma, 34, 73–87 (1971).

    Article  CAS  Google Scholar 

  13. An Atlas of Mammalian Chromosomes (edit. by Hsu, T. C., and Benirschke, K.) (Springer-Verlag, Berlin, Heidelberg and New York, 1967).

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FAUST, J., VOGEL, W. Are ‘N bands’ selective staining of specific heterochromatin?. Nature 249, 352–353 (1974). https://doi.org/10.1038/249352a0

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