Abstract
RECENT work on the proteins of bacteriophage PM2 have led us to a model for the structure of this virus, proposed in this communication. Experimental results have enabled us to assign each of the four proteins1 to morphological structures of the virus revealed by electron microscopic and structural studies. Packing considerations indicate that protein II must form the outer protein shell2. Both proteins I and II are on the outside of the phage particle as demonstrated by labelling with radioactive iodine after lactoperoxidase treatment3 by the method of Phillips and Morrison4,5.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Datta, A., Camerini-Otero, R. D., Braunstein, S. N., and Franklin, R. M., Virology, 45, 232 (1971).
Harrison, S. C., Caspar, D. L. D., Camerini-Otero, R. D., and Franklin, R. M., Nature new Biol., 229, 197 (1971).
Braunstein, S. N., thesis, New York Univ. School of Medicine (1972).
Phillips, D. R., and Morrison, M., Biochem. biophys. Res. Commun., 40, 284 (1970).
Phillips, D. R., and Morrison, M., Biochemistry, N.Y., 10, 1766 (1971).
Berg, H. C., Biochim. biophys. Acta, 183, 65 (1969).
Camerini-Otero, R. D., Datta, A., and Franklin, R. M., Virology, 49, 522 (1972).
Braunstein, S. N., and Franklin, R. M., Virology, 43, 685 (1971).
Camerini-Otero, R. D., and Franklin, R. M., Virology, 49, 385 (1972).
Maddy, A. H., Biochim. biophys. Acta, 88, 390 (1964).
Bretscher, M. S., J. molec. Biol., 71, 523 (1972).
Tsukagoshi, N., and Franklin, R. M., Virology (in the press).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SCHAEFER, R., HINNEN, R. & FRANKLIN, R. Further observations on the structure of the lipid-containing bacteriophage PM2. Nature 248, 681–682 (1974). https://doi.org/10.1038/248681a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/248681a0
This article is cited by
-
Presence of nucleoside triphosphates and calcium associated with mycobacteriophage I3
Archives of Microbiology (1981)
-
Effect of unsaturated fatty acids on the lipid composition of bacteriophage PM2
Nature (1975)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.