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Chimaera mouse study shows absence of disease in genetically dystrophic muscle

Abstract

Chimaeras have been derived from aggregation of normal and dystrophic mouse embryos which had healthy muscles of almost totally dystrophic genotype, and diseased muscles of normal genotype. These results suggest that extramuscular factors must be implicated in muscular dystrophy.

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Peterson, A. Chimaera mouse study shows absence of disease in genetically dystrophic muscle. Nature 248, 561–564 (1974). https://doi.org/10.1038/248561a0

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