Abstract
THE major histocompatibility system of man, designated HL-1, includes a series of closely linked genes of diverse functions1. HL-1 includes loci controlling two closely linked genes for the segregant series of HL-A antigens, genes responsible for the stimulation in mixed lymphocyte reactions (MLR-S) and possibly a genetic determinant (s) important for the induction of delayed-type hypersensitivity responses (HDR)2,3. Recombination between the genes for HL-A and between HL-A and MLR-S has been reported2,3.
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References
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YUNIS, E., KRIVIT, W., REINSMOEN, N. et al. Inheritance of a recombinant HL-A haplotype and genetics of the HL-1 region in man. Nature 248, 517–519 (1974). https://doi.org/10.1038/248517a0
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DOI: https://doi.org/10.1038/248517a0
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