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Changes in a surface-labelled galactoprotein and in glycolipid concentrations in cells transformed by a temperature-sensitive polyoma virus mutant

Abstract

IN hamster cells transformed by a temperature-sensitive mutant of polyoma virus we have found that the external label in a galactoprotein disappears and the cellular concentration of lactosylceramide increases when the cells are grown at the permissive temperature. These changes can be reversed at the non-permissive temperature.

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GAHMBERG, C., KIEHN, D. & HAKOMORI, SI. Changes in a surface-labelled galactoprotein and in glycolipid concentrations in cells transformed by a temperature-sensitive polyoma virus mutant. Nature 248, 413–415 (1974). https://doi.org/10.1038/248413a0

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