Article | Published:

Lateral diffusion of rhodopsin in the photoreceptor membrane

Naturevolume 247pages438441 (1974) | Download Citation

Subjects

Abstract

Rhodopsin undergoes rapid lateral diffusion in the disk membranes of isolated frog and mudpuppy rods. The rate of lateral diffusion is consistent with the rapid rotational diffusion of rhodopsin: both indicate the disk membrane is highly fluid with a viscosity of 1P.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Cone, R. A., Nature new Biol., 236, 39 (1972).

  2. 2

    Blasie, J. K., and Worthington, C. R., J. molec. Biol., 39, 417 (1969).

  3. 3

    Frye, L. D., and Edidin, M., J. Cell Sci., 7, 319 (1970).

  4. 4

    Pinto da Silva, P., J. Cell Biol., 53, 777 (1972).

  5. 5

    Speth, V., and Wunderlich, F., Biochm. biophys. Acta, 291, 621 (1973).

  6. 6

    Taylor, R. B., Duffus, W. P. H., Raff, M. C., and dePetris, S., Nature new Biol., 233, 225 (1971).

  7. 6a

    Edidin, M., and Famborough, D., J. Cell Biol., 57, 27 (1973).

  8. 7

    Brown, P. K., Nature new Biol., 236, 35 (1972).

  9. 8

    Wald, G., and Brown, P. K., J. gen. Physiol., 37, 189 (1953).

  10. 9

    Blasie, J. K., Worthington, C. R., and Dewey, M. M., J. molec. Biol., 39, 407 (1969).

  11. 10

    Blasie, J. K., and Worthington, C. R., J. molec. Biol., 39, 417 (1969).

  12. 11

    Guzzo, A. V., and Pool, F. L., Science, 159, 312 (1968).

  13. 12

    Busch, G. E., Applebury, M. L., Lamola, A. A., and Rentzepis, P. M., Proc. nat. Acad. Sci., U.S.A., 69, 2802 (1972).

  14. 13

    Poo, M. M., and Cone, R. A., Expl. Eye Res. (in the press).

  15. 14

    Young, R. W., J. Cell Biol., 33, 61 (1967).

  16. 15

    Cohen, A. I., in Handbook of Sensory Physiology, edit. Fuortes, M. G. F., 7/2, 73 (Springer, Heidelberg, 1972).

  17. 16

    Einstein, A., Ann. Physik., (4) 17, 549 (1905).

  18. 17

    Sutherland, G. B. B. M., Phil. Mag., 9, 781 (1905).

  19. 18

    Stryer, L., Renthal, R., and Steinemann, A., Exp. Eye Res., (in the press).

  20. 19

    Hubbell, W. W., Hong, K., and Chen, Y. S., Exp. Eye Res., (in the press).

  21. 20

    Hubbard, R. J., J. gen. Physiol., 37, 381 (1954).

  22. 21

    Singer, S. J., and Nicholson, G., Science, 175, 720 (1972).

  23. 22

    Keith, A., Bulfield, G., and Snipes, W., Biophys. J., 10, 618 (1970).

  24. 23

    Calvin, M., Wang, H. H., Entine, G., Gill, D., Ferruti, P., Harikdm, M. A., and Klein, M. P., Proc. natl. Acad. Sci. U.S.A., 63, 1 (1969).

  25. 24

    Scandella, C. J., Devaux, P., and McConnell, H. M., Proc. natl. Acad. Sci., U.S.A., 69, 2056 (1972).

  26. 25

    Hong, K., and Hubbell, W. L., Proc. natl. Acad. Sci., U.S.A., 69, 2617 (1972).

  27. 26

    Chabre, M., Cavaggioni, A., Osborne, H. B., Gulik- Krzywicki, T., and Olive, J., FEBS. Lett., 26, 197 (1972).

  28. 27

    Montal, M., and Korenbrot, J. I., Nature, 246, 219 (1973).

Download references

Author information

Affiliations

  1. The Thomas C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, Maryland, 21218

    • Mu-ming Poo
    •  & Richard A. Cone

Authors

  1. Search for Mu-ming Poo in:

  2. Search for Richard A. Cone in:

About this article

Publication history

Received

Accepted

Issue Date

DOI

https://doi.org/10.1038/247438a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.