Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Lateral diffusion of rhodopsin in the photoreceptor membrane

Abstract

Rhodopsin undergoes rapid lateral diffusion in the disk membranes of isolated frog and mudpuppy rods. The rate of lateral diffusion is consistent with the rapid rotational diffusion of rhodopsin: both indicate the disk membrane is highly fluid with a viscosity of 1P.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Cone, R. A., Nature new Biol., 236, 39 (1972).

    Article  CAS  Google Scholar 

  2. Blasie, J. K., and Worthington, C. R., J. molec. Biol., 39, 417 (1969).

    Article  CAS  Google Scholar 

  3. Frye, L. D., and Edidin, M., J. Cell Sci., 7, 319 (1970).

    CAS  PubMed  Google Scholar 

  4. Pinto da Silva, P., J. Cell Biol., 53, 777 (1972).

    Article  CAS  Google Scholar 

  5. Speth, V., and Wunderlich, F., Biochm. biophys. Acta, 291, 621 (1973).

    Article  CAS  Google Scholar 

  6. Taylor, R. B., Duffus, W. P. H., Raff, M. C., and dePetris, S., Nature new Biol., 233, 225 (1971).

    Article  CAS  Google Scholar 

  7. Edidin, M., and Famborough, D., J. Cell Biol., 57, 27 (1973).

    Article  CAS  Google Scholar 

  8. Brown, P. K., Nature new Biol., 236, 35 (1972).

    Article  ADS  CAS  Google Scholar 

  9. Wald, G., and Brown, P. K., J. gen. Physiol., 37, 189 (1953).

    Article  CAS  Google Scholar 

  10. Blasie, J. K., Worthington, C. R., and Dewey, M. M., J. molec. Biol., 39, 407 (1969).

    Article  CAS  Google Scholar 

  11. Blasie, J. K., and Worthington, C. R., J. molec. Biol., 39, 417 (1969).

    Article  CAS  Google Scholar 

  12. Guzzo, A. V., and Pool, F. L., Science, 159, 312 (1968).

    Article  ADS  CAS  Google Scholar 

  13. Busch, G. E., Applebury, M. L., Lamola, A. A., and Rentzepis, P. M., Proc. nat. Acad. Sci., U.S.A., 69, 2802 (1972).

    Article  ADS  CAS  Google Scholar 

  14. Poo, M. M., and Cone, R. A., Expl. Eye Res. (in the press).

  15. Young, R. W., J. Cell Biol., 33, 61 (1967).

    Article  CAS  Google Scholar 

  16. Cohen, A. I., in Handbook of Sensory Physiology, edit. Fuortes, M. G. F., 7/2, 73 (Springer, Heidelberg, 1972).

    Google Scholar 

  17. Einstein, A., Ann. Physik., (4) 17, 549 (1905).

    Article  ADS  CAS  Google Scholar 

  18. Sutherland, G. B. B. M., Phil. Mag., 9, 781 (1905).

    Article  CAS  Google Scholar 

  19. Stryer, L., Renthal, R., and Steinemann, A., Exp. Eye Res., (in the press).

  20. Hubbell, W. W., Hong, K., and Chen, Y. S., Exp. Eye Res., (in the press).

  21. Hubbard, R. J., J. gen. Physiol., 37, 381 (1954).

    Article  CAS  Google Scholar 

  22. Singer, S. J., and Nicholson, G., Science, 175, 720 (1972).

    Article  ADS  CAS  Google Scholar 

  23. Keith, A., Bulfield, G., and Snipes, W., Biophys. J., 10, 618 (1970).

    Article  CAS  Google Scholar 

  24. Calvin, M., Wang, H. H., Entine, G., Gill, D., Ferruti, P., Harikdm, M. A., and Klein, M. P., Proc. natl. Acad. Sci. U.S.A., 63, 1 (1969).

    Article  ADS  CAS  Google Scholar 

  25. Scandella, C. J., Devaux, P., and McConnell, H. M., Proc. natl. Acad. Sci., U.S.A., 69, 2056 (1972).

    Article  ADS  CAS  Google Scholar 

  26. Hong, K., and Hubbell, W. L., Proc. natl. Acad. Sci., U.S.A., 69, 2617 (1972).

    Article  ADS  CAS  Google Scholar 

  27. Chabre, M., Cavaggioni, A., Osborne, H. B., Gulik- Krzywicki, T., and Olive, J., FEBS. Lett., 26, 197 (1972).

    Article  CAS  Google Scholar 

  28. Montal, M., and Korenbrot, J. I., Nature, 246, 219 (1973).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Poo, Mm., Cone, R. Lateral diffusion of rhodopsin in the photoreceptor membrane. Nature 247, 438–441 (1974). https://doi.org/10.1038/247438a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/247438a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing