Letter | Published:

Group analysis of volatile and non-volatile N-nitroso compounds

Naturevolume 247pages309310 (1974) | Download Citation

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Abstract

THERE is much concern about the possible widespread occurrence of N-nitroso compounds in the environment1. Many N-nitroso compounds are known to be carcinogenic2,3, and some ‘Volatile’ nitrosamines have been found in cured food products such as smoked fish4–6, cooked bacon (ref. 5 and United States Department of Agriculture News Release, 1972), and sausages5. N-nitroso compounds are generally unstable and have a wide range of physical properties, particularly with respect to volatility and solubility.

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References

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    Lijinsky, W., and Epstein, S. S., Nature, 225, 21 (1970).

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    Magee, P., and Barnes, J., Adv. Cancer Res., 10, 164 (1967).

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    Druckrey, H., Preussman, R., and Ivanokovic, S., Ann. N.Y. Acad. Sci. 163, 676 (1969).

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    Fazio, T., Damico, J. N., Howard, J. W., White, R. H., and Watts, J. O., J. agric. Fd Chem., 19, 251 (1971).

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    Crosby, N. T., Foreman, J. K., Palframan, J. F., and Sawyer, R., Nature, 238, 342 (1972).

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    Sen, N. P., Smith, D. C., Schwinghamer, L., and Marleau, J. J., J. Assoc. analyt. Chem., 52, 47 (1969).

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    Essigmann, J. M., and Issenberg, P., J. Fd Sci., 37, 684 (1972).

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    Telling, G. M., Bryce, T. A., and Althorpe, J., J. agric. Fd Chem., 19, 937 (1971).

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    Gough, T. A., and Webb, K. S., J. Chromatog., 79, 57 (1973).

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    Fine, D. H., and Rufeh, F., Description of the Thermoluminous Analyzer for N-nitroso compounds (International Agency for Research on Cancer, Third Meeting on the Analysis and Formation of N-Nitroso Compounds, Lyon, 1973, in the press).

  11. 11

    Fine, D. H., Rufeh, F., and Gunther, B., Analyt. Lett. 6, 731 (1973).

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Affiliations

  1. Thermo Electron Corporation, 85 First Avenue, Waltham, Massachusetts, 02154

    • D. H. FINE
    • , F. RUFEH
    •  & D. LIEB

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https://doi.org/10.1038/247309a0

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