Letter | Published:

Group analysis of volatile and non-volatile N-nitroso compounds

Naturevolume 247pages309310 (1974) | Download Citation



THERE is much concern about the possible widespread occurrence of N-nitroso compounds in the environment1. Many N-nitroso compounds are known to be carcinogenic2,3, and some ‘Volatile’ nitrosamines have been found in cured food products such as smoked fish4–6, cooked bacon (ref. 5 and United States Department of Agriculture News Release, 1972), and sausages5. N-nitroso compounds are generally unstable and have a wide range of physical properties, particularly with respect to volatility and solubility.

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    Crosby, N. T., Foreman, J. K., Palframan, J. F., and Sawyer, R., Nature, 238, 342 (1972).

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    Essigmann, J. M., and Issenberg, P., J. Fd Sci., 37, 684 (1972).

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    Gough, T. A., and Webb, K. S., J. Chromatog., 79, 57 (1973).

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    Fine, D. H., and Rufeh, F., Description of the Thermoluminous Analyzer for N-nitroso compounds (International Agency for Research on Cancer, Third Meeting on the Analysis and Formation of N-Nitroso Compounds, Lyon, 1973, in the press).

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    Fine, D. H., Rufeh, F., and Gunther, B., Analyt. Lett. 6, 731 (1973).

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  1. Thermo Electron Corporation, 85 First Avenue, Waltham, Massachusetts, 02154

    • D. H. FINE
    • , F. RUFEH
    •  & D. LIEB


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