Abstract
The rate of nucleotide change between globin genes for mouse, rabbit, rat and man is considerably slower than that of non-repeated DNA, suggesting that selection pressure is less stringent on the bulk of the genome than on genes coding for polypeptides.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kimura, M., Nature, 217, 624–626 (1968).
McCarthy, B. J., and Farquhar, M. N., Brookhaven Symp. Biol., 23, 1–42 (1971).
Britten, R. J., and Davidson, E. H., Science, N.Y., 165, 349–357 (1969).
Georgiev, G. P., J. theor. Biol., 25, 473–490 (1969).
Crick, F., Nature, 234, 25–27 (1971).
Paul, J., Nature, 238, 444–446 (1972).
Harrison, P. R., Hell, A., Birnie, G. D., and Paul, J., Nature, 239, 219–221 (1972).
Packman, S., Aviv, H., Ross, J., and Leder, P., Biochem. biophys. Res. Commun., 49, 813–819 (1972).
Bishop, J. O., Pemberton, R., and Baglioni, C., Nature new Biol., 235, 231–234 (1972).
Bishop, J. O., and Rosbash, M., Nature new Biol., 241, 204–207 (1973).
McConaughy, B. L., and McCarthy, B. J., Biochem. Genet., 4, 425–446 (1970).
Kohne, D. E., Q. Rev. Biophys., 33, 327 (1970).
Lockard, R. E., and Lingrel, J. B., J. biol. Chem., 247, 4174–4179 (1972).
Williamson, R., Morrison, M., Lanyon, G., Eason, R., and Paul, J., Biochemistry, 10, 3014–3021 (1971).
Aviv, H., and Leder, P., Proc. natn. Acad. Sci., U.S.A., 69, 1408–1412 (1972).
Adesnik, M., Salditt, M., Thomas, W., and Darnell, J. E., J. molec. Biol., 71, 21 (1972).
Kacian, D. L., Watson, K. F., Burny, A., and Spiegelman, S., Biochim. biophys. Acta, 246, 365–383 (1971).
Harrison, P. R., Birnie, G. D., Hell, A., Humphries, S., Young, B., and Paul, J., J. molec. Biol., (in the press).
Sutton, W. O., Biochim. biophys. Acta, 240, 522–531 (1971).
Britten, R. J., and Kohne, D. E., Science, N.Y., 161, 529–540 (1968).
Laird, C. D., McConaughy, B. L., and McCarthy, B. J., Nature, 224, 149–154 (1969).
Bollum, F. J., in Meth. in Enzymology, 12B, 591–611 (1968).
Dayhoff, M. O., Atlas of Protein Sequence and Structure D-53-54, (National Biomedical Research Foundation, Washington, DC, 1972).
Leder, P., Aviv, H., Gielen, J., Ikawa, Y., Packman, S., Swan, D., and Ross, J., Cold Spring Harb. Symp. quant. Biol., 38, (in the press).
Birnstiel, M. L., Weinberg, E. S., and Pardue, M. L., Gatlinburg Conference Proceedings, 173, (in the press).
Housman, D., Forget, B. F., Skoultchi, A., and Benz, E. J., Proc. natn. Acad. Sci., U.S.A., 70, 1809–1813 (1973).
Marotta, C., Verma, I. M., McCaffrey, R. P., and Forget, B. F., Fed. Proc., 32, 455 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gummerson, K., Williamson, R. Sequence divergence of mammalian globin messenger RNA. Nature 247, 265–267 (1974). https://doi.org/10.1038/247265a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/247265a0
This article is cited by
-
Evolution of human Y-chromosome DNA
Chromosoma (1982)
-
Macronuclear DNA organization and transcription in Paramecium primaurelia
Chromosoma (1980)
-
Multiplicity of germline genes specifying a group of related mouse κ chains with implications for the generation of immunoglobulin diversity
Nature (1978)
-
Transcription of genetic information in amphibian oocytes
Chromosoma (1976)
-
Unique and repetitive sequences in multiple genes for feather keratin
Nature (1975)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.