Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effect of Blood Flow Velocity on Growth Rate of Platelet Thrombi

Abstract

ACUTE thrombogenesis in a flowing bloodstream can occur on damaged tissues in the normal circulation, especially on exposure to collagen, and over surfaces of vascular prostheses and artificial internal organs1–3. The thrombi are composed predominantly of platelets. Begent and Born4 have obtained quantitative data on growth rates of such thrombi produced in vivo.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hugues, J., Thrombos. Diasthes. Haemorrh., 3, 177 (1959).

    Article  Google Scholar 

  2. Porter, K. A., J. clin. Path. Suppl., 20, 518 (1967).

    Google Scholar 

  3. Akutsu, T., and Takagi, H., Trans. Am. Soc. Art. Intern. Organs, 15, 55 (1969).

    CAS  Google Scholar 

  4. Begent, N., and Born, G. V. R., Nature, 227, 926 (1970).

    Article  ADS  CAS  Google Scholar 

  5. Friedman, L. I., et al., Trans. Am. Soc. Art. Intern. Organs, 16, 63 (1970).

    CAS  Google Scholar 

  6. Macmillan, D. C., Nature, 211, 140 (1966).

    Article  ADS  CAS  Google Scholar 

  7. Meksyn, D., New Methods in Laminar Boundary Layer Theory (Pergamon, 1961).

    Google Scholar 

  8. Lighthill, M. J., Proc. R. Soc., A, 202, 359 (1950).

    ADS  CAS  Google Scholar 

  9. Born, G. V. R., J. Physiol., 209, 487 (1970).

    Article  CAS  Google Scholar 

  10. Levich, V. G., Physicochemical Hydrodynamics (Prentice-Hall, 1962).

  11. Goldsmith, H. L., and Mason, S. G., in Rheology—Theory and Applications, 4, chap. 2 (Academic Press, 1967).

    Google Scholar 

  12. Richardson, P. D., Bull. NY Acad. Med., 48, 379 (1972).

    CAS  Google Scholar 

  13. Monsler, M., Morton, W., and Weiss, R., AAIA Paper, 70 (1970).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

RICHARDSON, P. Effect of Blood Flow Velocity on Growth Rate of Platelet Thrombi. Nature 245, 103–104 (1973). https://doi.org/10.1038/245103a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/245103a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing