Abstract
ACUTE thrombogenesis in a flowing bloodstream can occur on damaged tissues in the normal circulation, especially on exposure to collagen, and over surfaces of vascular prostheses and artificial internal organs1–3. The thrombi are composed predominantly of platelets. Begent and Born4 have obtained quantitative data on growth rates of such thrombi produced in vivo.
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References
Hugues, J., Thrombos. Diasthes. Haemorrh., 3, 177 (1959).
Porter, K. A., J. clin. Path. Suppl., 20, 518 (1967).
Akutsu, T., and Takagi, H., Trans. Am. Soc. Art. Intern. Organs, 15, 55 (1969).
Begent, N., and Born, G. V. R., Nature, 227, 926 (1970).
Friedman, L. I., et al., Trans. Am. Soc. Art. Intern. Organs, 16, 63 (1970).
Macmillan, D. C., Nature, 211, 140 (1966).
Meksyn, D., New Methods in Laminar Boundary Layer Theory (Pergamon, 1961).
Lighthill, M. J., Proc. R. Soc., A, 202, 359 (1950).
Born, G. V. R., J. Physiol., 209, 487 (1970).
Levich, V. G., Physicochemical Hydrodynamics (Prentice-Hall, 1962).
Goldsmith, H. L., and Mason, S. G., in Rheology—Theory and Applications, 4, chap. 2 (Academic Press, 1967).
Richardson, P. D., Bull. NY Acad. Med., 48, 379 (1972).
Monsler, M., Morton, W., and Weiss, R., AAIA Paper, 70 (1970).
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RICHARDSON, P. Effect of Blood Flow Velocity on Growth Rate of Platelet Thrombi. Nature 245, 103–104 (1973). https://doi.org/10.1038/245103a0
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DOI: https://doi.org/10.1038/245103a0
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