Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Ethanol and Methanol Metabolites in Alcohol Withdrawal

Abstract

THE twenty-one subjects participating in this study were serial admissions to the St Louis Detoxification Center during the period of December 2–21, 1971. Their ages ranged from 29 to 72 yr and they comprised twenty males and one female. A blood sample (10 ml) was obtained from the patient on admission, when a symptom intensity rating evaluation was carried out1,2. Blood concentrations of ethanol, methanol, acetaldehyde and formaldehyde-formate were determined by gas-liquid chromatography3,4. This procedure was repeated on four consecutive days (total of five samples), after which the patient was discharged from the Center.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Gross, M. M., Rosenblatt, S. M., Chartoff, S., Herman, A., Schacter, M., Sheinkin, D., and Broman, M., Quart. J. Stud. Alcohol, 32, 611 (1971).

    CAS  PubMed  Google Scholar 

  2. Gross, M. M., Eastlyn, L., Meena, N., and Hastey, S. M., in Biology of Alcoholism, 3 (edit. by Kissin, B., and Begleiter, H.) (Plenum, New York, in the press).

  3. Steinberg, M., J. Foren. Sci., 10, 201 (1965).

    CAS  Google Scholar 

  4. Goldbaum, L. R., J. Foren. Sci., 9, 63 (1964).

    CAS  Google Scholar 

  5. Kaim, S. C., Klett, C. S., and Rothfeld, B., Amer. J. Psych., 125, 12 (1969).

    Article  Google Scholar 

  6. Klett, C. S., Hollister, L. E., Caffey, jun., E. M., and Kaim, S. C., Arch. Gen. Psych., 24, 174 (1971).

    Article  CAS  Google Scholar 

  7. Snedecor, G. A., Statistical Methods, 106 (Iowa State College G.W. Press, Ames, Iowa, 1955).

    Google Scholar 

  8. Majchrowicz, E., and Mendelson, J. H., J. Pharmacol. Exper. Therap., 179, 298 (1971).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MAGRINAT, G., DOLAN, J., BIDDY, R. et al. Ethanol and Methanol Metabolites in Alcohol Withdrawal. Nature 244, 234–235 (1973). https://doi.org/10.1038/244234a0

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/244234a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing