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Acetylcholine Release within the Cat Striatum during the Sleep–Wakefulness Cycle

Nature volume 243, pages 518–519 (1973)Cite this article

Abstract

THE caudate nucleus (CN) is a subcortical region rich in acetylcholine (ACh)1. Considering the role played by this nucleus2 in sensorimotor control, changes in its cholinergic activity could occur during different stages of sleep (S) and wakefulness (W). Involvement of the CN in the S-W cycle is likely as electrical stimulation of the neostriatum results in S in various species3–5. We have therefore investigated the ACh output from caudate neurones during W, slow-wave sleep (SWS) and paradoxical sleep (PS) using chronic push-pull cannulae.

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Author notes

  1. M. GADEA-CIRIA

    Present address: Departamento de Neurologia, Gran Hospital del Estado, Madrid, Spain

Authors and Affiliations

  1. Medical Research Department, F. Hoffmann-La Roche and Co. Ltd, 4002, Basle

    M. GADEA-CIRIA, H. STABLER, K. G. LLOYD & G. BARTHOLINI

Authors
  1. M. GADEA-CIRIA
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  2. H. STABLER
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  3. K. G. LLOYD
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  4. G. BARTHOLINI
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GADEA-CIRIA, M., STABLER, H., LLOYD, K. et al. Acetylcholine Release within the Cat Striatum during the Sleep–Wakefulness Cycle. Nature 243, 518–519 (1973). https://doi.org/10.1038/243518a0

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