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Oxidative Phosphorylation in Adult Schistosoma mansoni

Abstract

THE blood fluke, Schistosoma mansoni, takes up large quantities of glucose and excretes lactic acid. It also uses oxygen but the role of this oxygen uptake in the metabolism of adult schistosomes is unclear. No increase in the rate of lactic acid excretion was observed when the worms were incubated under nitrogen and it was assumed that the flukes obtain all their energy by glycolysis1. Further studies suggested that there were only sufficient cytochromes present to account for 1/10 of the oxygen uptake of the worms2 and cyanine dyes inhibited 50% of the oxygen uptake without apparently adversely affecting them3.

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References

  1. Bueding, E., J. Gen. Physiol., 33, 475 (1950).

    Article  CAS  Google Scholar 

  2. Bueding, E., and Charms, B., J. Biol. Chem., 196, 615 (1952).

    CAS  PubMed  Google Scholar 

  3. Bueding, E., Peters, L., Koletsky, S., and Moore, D. V., Brit. J. Pharmacol., 8, 15 (1953).

    CAS  PubMed  Google Scholar 

  4. Coles, G. C., J. Parasit., 2, 341 (1972).

    CAS  Google Scholar 

  5. Clegg, J. A., and Smithers, S. R., J. Parasit., 2, 79 (1972).

    CAS  Google Scholar 

  6. Ross, O. A., and Bueding, E., Proc. Soc. Exp. Biol. Med., 73, 179 (1950).

    Article  Google Scholar 

  7. Waitz, A. M., Life Sci., 3, 377 (1964).

    Article  CAS  Google Scholar 

  8. Coles, G. C., Comp. Biochem. Physiol., 34, 213 (1970).

    Article  ADS  CAS  Google Scholar 

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COLES, G. Oxidative Phosphorylation in Adult Schistosoma mansoni. Nature 240, 488–489 (1972). https://doi.org/10.1038/240488a0

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