Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Correspondence
  • Published:

Remission of adult acute lymphocytic leukaemia with Alemtuzumab

Leukemia volume 18, pages 1557–1558 (2004)Cite this article

TO THE EDITOR

Despite recent improvement in chemotherapy and haemopoietic stem cell transplantation, the prognosis of acute lymphocytic leukaemia (ALL) in adults remains poor. In patients who have relapsed, following a first remission, the probability of cure is almost nil with conventional chemotherapy only.1

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Hoelzer D, Gokbuget N, Ottmann O, Pui CH, Relling MV, Appelbaum FR et al. Acute lymphoblastic leukemia. Am Soc Haematol Educat Prog 2002, 162–192.

  2. Hale G, Bright S, Chumbley G, Hoang T, Metcalf D, Munro AJ et al. Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement. Blood 1983; 62: 873–882.

    CAS  Google Scholar 

  3. Zhang Z, Zhang M, Goldman CK, Ravetch JV, Waldmann TA . Effective therapy for a murine model of adult T-cell leukemia with the humanized anti-CD52 monoclonal antibody, Campath-1H. Cancer Res 2003; 63: 6453–6457.

    CAS  PubMed  Google Scholar 

  4. Keating MJ, Cazin B, Coutre S, Birhiray R, Kovacsovics T, Langer W et al. Campath-1H treatment of T-cell prolymphocytic leukemia in patients for whom at least one prior chemotherapy regimen has failed. J Clin Onc 2002; 20: 205–213.

    Article  CAS  Google Scholar 

  5. Dearden CE, Matutes E, Cazin B, Tjonnfjord GE, Parreira A, Nomdedeu B et al. High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H. Blood 2001; 98: 1721–1726.

    Article  CAS  Google Scholar 

  6. Boissel N, Auclerc MF, Lheritier V, Perel Y, Thomas X, Leblanc T et al. Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults? Comparison of the French FRALLE-93 and LALA-94 trials. J Clin Oncol 2003; 21: 760–761.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of hematology and cell therapy, Centre hospitalo-universitaire Saint-Antoine and Université Paris 6, 184 rue du Faubourg Saint-Antoine, Paris, France

    J P Laporte, F Isnard, L Garderet, L Fouillard & N-C Gorin

Authors
  1. J P Laporte
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F Isnard
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L Garderet
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. L Fouillard
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. N-C Gorin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to J P Laporte.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Laporte, J., Isnard, F., Garderet, L. et al. Remission of adult acute lymphocytic leukaemia with Alemtuzumab. Leukemia 18, 1557–1558 (2004). https://doi.org/10.1038/sj.leu.2403422

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.leu.2403422

This article is cited by

Search

Advanced search

Quick links