Abstract
THE relationship between late DNA replication and X chromosome inactivation is supported by strong circumstantial evidence1–3. The use of clones derived from a female mule1 typed for Gd and at the same passage labelled with 3H-TdR and subsequently autoradiographed should provide final proof of this relationship.
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References
Hamerton, J. L., Richardson, B. J., Gee, P. A., Allen, W. R., and Short, R. V., Nature, 232, 312 (1971).
Giannelli, F., and Hamerton, J. L., Nature, 232, 315 (1971).
Cohen, M. M., and Rattazzi, M. C., Proc. US Nat. Acad. Sci., 68, 544 (1971).
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RAY, M., GEE, P., RICHARDSON, B. et al. G6PD Expression and X Chromosome Late Replication in Fibroblast Clones from a Female Mule. Nature 237, 396–397 (1972). https://doi.org/10.1038/237396a0
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DOI: https://doi.org/10.1038/237396a0
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