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G6PD Expression and X Chromosome Late Replication in Fibroblast Clones from a Female Mule

Abstract

THE relationship between late DNA replication and X chromosome inactivation is supported by strong circumstantial evidence1–3. The use of clones derived from a female mule1 typed for Gd and at the same passage labelled with 3H-TdR and subsequently autoradiographed should provide final proof of this relationship.

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References

  1. Hamerton, J. L., Richardson, B. J., Gee, P. A., Allen, W. R., and Short, R. V., Nature, 232, 312 (1971).

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  2. Giannelli, F., and Hamerton, J. L., Nature, 232, 315 (1971).

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  3. Cohen, M. M., and Rattazzi, M. C., Proc. US Nat. Acad. Sci., 68, 544 (1971).

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RAY, M., GEE, P., RICHARDSON, B. et al. G6PD Expression and X Chromosome Late Replication in Fibroblast Clones from a Female Mule. Nature 237, 396–397 (1972). https://doi.org/10.1038/237396a0

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