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Occurrence of Heterozygotes and Homozygotes for the α-Chain Haemoglobin Variant Hb-J(Tongariki) in New Guinea

Abstract

THE occurrence of the haemoglobin Hb-J(Tongariki) in new locations in the New Guinea area is of interest because this α-chain variant was the first to be found in Melanesian populations. Furthermore, the high proportion of the variant in heterozygotes and the discovery of three apparently homozygous subjects with Hb-J(Tongariki) as the sole major haemoglobin are relevant to current discussion concerning the possible duplication of the human α-chain gene locus.

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BEAVEN, G., HORNABROOK, R., FOX, R. et al. Occurrence of Heterozygotes and Homozygotes for the α-Chain Haemoglobin Variant Hb-J(Tongariki) in New Guinea. Nature 235, 46–47 (1972). https://doi.org/10.1038/235046a0

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