Abstract
A VEGETALIZING protein isolated from 9 day old chicken embryos1–3 and implanted into the blastocoel of an early Triturus gastrula4 induces the ectoderm of the host embryo to form mesodermal tissues (muscle, notochord, renal tubes). Larger quantities of this highly purified factor cause the invaginated endoderm to exovaginate and spread over the induced ectoderm at the end of gastrulation. This may result from a change of cell affinities in the induced ectoderm5. In the exovagination series voluminous mesodermal and endodermal structures have been shown to develop from gastrula ectoderm under the influence of the implanted substance (U. K.-B., unpublished).
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KOCHER-BECKER, U., TIEDEMANN, H. Induction of Mesodermal and Endodermal Structures and Primordial Germ Cells in Triturus Ectoderm by a Vegetalizing Factor from Chick Embryos. Nature 233, 65–66 (1971). https://doi.org/10.1038/233065a0
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DOI: https://doi.org/10.1038/233065a0
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