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Enhancement of Residual Antibody Synthesis by Irradiation of the Spleen in Pre-immunized Rats

Nature volume 229, pages 263–264 (1971)Cite this article

Abstract

STIMULATION of the immune response by localized irradiation has been observed by several investigators1–3. In all these studies, however, radiation was administered soon after antigen injection. In these experiments we have therefore examined whether localized irradiation of a lymphoid organ some time after antigen injection has a similar effect on residual antibody production. The effects of irradiation of the exposed spleen (with body shielding) on residual titres were studied in rats irradiated several weeks after a priming injection of sheep red blood cells (SRBC).

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References

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Authors and Affiliations

  1. Institute for Biological Research, Belgrade

    MIROSLAV M. SIMIĆ

  2. Faculty of Pharmacy, University of Belgrade,

    MILICA Ž. PETROVIĆ

Authors
  1. MIROSLAV M. SIMIĆ
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  2. MILICA Ž. PETROVIĆ
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SIMIĆ, M., PETROVIĆ, M. Enhancement of Residual Antibody Synthesis by Irradiation of the Spleen in Pre-immunized Rats. Nature 229, 263–264 (1971). https://doi.org/10.1038/229263a0

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  • DOI: https://doi.org/10.1038/229263a0

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