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Properties, Structure and Possible Neuroreceptor Role of the Encephalitogenic Protein of Human Brain

Nature volume 229, pages 25–28 (1971)Cite this article

Abstract

The principal determinant region of the encephalitogenic protein, the amino-acids of which have been sequenced, is located round the sole tryptophan residue. The determinant may be the receptor site for 5-hydroxytryptamine in certain regions of the central nervous system, and the paralysis in experimental autoimmune encephalomyelitis may be caused by an immunopharmacological block of nervous transmission.

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Authors and Affiliations

  1. Russell Grimwade School of Biochemistry, University of Melbourne, Parkville, Victoria, 3052

    P. R. CARNEGIE

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  1. P. R. CARNEGIE
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CARNEGIE, P. Properties, Structure and Possible Neuroreceptor Role of the Encephalitogenic Protein of Human Brain. Nature 229, 25–28 (1971). https://doi.org/10.1038/229025a0

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