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Antibody Response to Tumour Xenografts in Mice treated with Antilymphocyte Serum

Abstract

ANTILYMPHOCYTE serum (ALS) has been shown to suppress the cell mediated response to tissue grafts1, but its effect on the humoral response is less marked2. A system for assessing the effect of ALS on the humoral response to xenografts is provided by the human tumour line HeLa grown in mice treated with ALS3. We have therefore studied the antibody response to HeLa cells in mice treated with ALS and bearing HeLa cell tumours, using a fluorescent antibody technique.

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PHILLIPS, B., GAZET, JC. Antibody Response to Tumour Xenografts in Mice treated with Antilymphocyte Serum. Nature 228, 369–370 (1970). https://doi.org/10.1038/228369a0

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