Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Protein Degradation and Synthesis in Amino-acid Deficiencies

Abstract

IT is well known that most body proteins are continually degraded and resynthesized. The protein content of various organs must represent the net balance between synthesis and degradation over some period of time. Nutritional or other factors which influence the protein content of tissues might act on either protein synthesis or degradation or both.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Schimke, R. T., J. Biol. Chem., 239, 3808 (1964).

    CAS  PubMed  Google Scholar 

  2. Schimke, R. T., in Mammalian Protein Metabolism (edit. by Munro, H. N.) (Academic Press, in the press).

  3. Neuberger, A., and Bichards, F. F., in Mammalian Protein Metabolism (edit. by Munro, H. N., and Allison, J. B.), 1 (Academic Press, 1964).

    Google Scholar 

  4. Waterlow, J. C., and Stephen, J. M. L., Clin. Sci., 35, 287 (1968).

    CAS  PubMed  Google Scholar 

  5. Gan, J. C., and Jeffay, H., Biochim. Biophys. Acta, 148, 448 (1967).

    Article  CAS  Google Scholar 

  6. Goldberg, A. L., J. Biol. Chem., 244, 3217 (1969).

    CAS  PubMed  Google Scholar 

  7. Goldberg, A. L., J. Biol. Chem., 244, 3223 (1969).

    CAS  PubMed  Google Scholar 

  8. Nutrition Rev., 28, 45 (1970).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

FASHAKIN, J., HEGSTED, D. Protein Degradation and Synthesis in Amino-acid Deficiencies. Nature 228, 1313–1314 (1970). https://doi.org/10.1038/2281313a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2281313a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing