Abstract
A new component, “J” (for joining), has been found in rabbit and human secretory IgA in addition to the S, α, and light chains already characterized. J has a molecular weight of approximately 23,000 and, by contrast with the S component, is disulphide-linked to the α chain. It is present in the dimer but not the monomer form of human IgA myelomas, and therefore seems to be responsible for the dimer structure characteristic of secretory IgA.
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HALPERN, M., KOSHLAND, M. Novel Subunit in Secretory IgA. Nature 228, 1276–1278 (1970). https://doi.org/10.1038/2281276a0
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DOI: https://doi.org/10.1038/2281276a0
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