Abstract
INTERFERON induces a cytotoxic effect in normal mouse spleen cells against allogeneic tumour target cells in tissue culture1,2. We here present evidence that syngeneic lymphoid cells may be similarly activated by interferon and that syngeneic lymphoid cells plus interferon suppress the growth of tumour cells in vivo.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Svet-Moldavsky, G. J., and Chernyakhovskaya, I. Yu., Proc. All-Union Conference on Transplantation of Organs and Tissues, Minsk., 359 (Medicine, Moscow, 1966) (in Russian).
Svet-Moldavsky, G. J., and Chernyakhovskaya, I. Yu., Nature, 215, 1299 (1967).
Earle, W. E., J. Nat. Cancer Inst., 4, 165 (1943).
Hare, J. D., and Morgan, H. R., J. Nat. Cancer Inst., 33, 765 (1964).
Levy, H. B., Law, L. W., and Rabson, A. S., Proc. US Nat. Acad. Sci., 62, 357 (1969).
Rhim, J. S., Greenawalt, C., and Huebner, R. J., Nature, 222, 1166 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CHERNYAKHOVSKAYA, I., SLAVINA, E. & SVET-MOLDAVSKY, G. Antitumour Effect of Lymphoid Cells activated by Interferon. Nature 228, 71–72 (1970). https://doi.org/10.1038/228071a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/228071a0
This article is cited by
-
Tumour cell lines induce interferon in human lymphocytes
Nature (1977)
-
Interferpnogenicity and Antigen Recognition
Nature (1974)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.