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Higher Bohr Effect in Indian Natives of Peruvian Highlands as compared with Europeans

Abstract

A CHANGE in the affinity of haemoglobin for oxygen is one of the mechanisms which have been considered to explain how man adapts himself to life at high altitudes1–5. These studies were performed, however, without considering a change in the Bohr effect—the decrease in affinity of haemoglobin for oxygen at lower tissue pH—as a possible mechanism of adaptation.

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MORPURGO, G., BATTAGLIA, P., BERNINI, L. et al. Higher Bohr Effect in Indian Natives of Peruvian Highlands as compared with Europeans. Nature 227, 387–388 (1970). https://doi.org/10.1038/227387a0

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