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Amino-acid Sequence of the Qβ Coat Protein

Nature volume 227, pages 271–273 (1970)Cite this article

Abstract

THE RNA phages provide an excellent system in which to determine the primary structure of a messenger RNA and relate this to the proteins which it codes1,2. By establishing the frame of reading, it is then possible to locate initiation and termination sites as well as extragenic regions3,4. Our previous work concerned the amino-acid sequences of the f2 and R17 coat proteins5,6. Using R17 it was possible to identify the initiation region corresponding to the coat protein cistron7; the termination region corresponding to the carboxy-terminus of the same cistron4; and an internal region of 57 nucleotides out of this cistron corresponding to residues 81–99 of the coat protein3.

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Author information

Author notes

  1. JON KATZE

    Present address: Department of Microbiology, University of Southern California, School of Medicine, Los Angeles, California

Authors and Affiliations

  1. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut

    WILLIAM KONIGSBERG, TETSUO MAITA & JON KATZE

  2. Biological Laboratories, Harvard University, Cambridge, Massachusetts

    KLAUS WEBER

Authors
  1. WILLIAM KONIGSBERG
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  2. TETSUO MAITA
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  3. JON KATZE
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  4. KLAUS WEBER
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KONIGSBERG, W., MAITA, T., KATZE, J. et al. Amino-acid Sequence of the Qβ Coat Protein. Nature 227, 271–273 (1970). https://doi.org/10.1038/227271a0

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