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Electrophoretic Mobility of Tumour Cells exposed to Ultrasound and Ionizing Radiation

Nature volume 227, pages 166–167 (1970)Cite this article

Abstract

THE degree of malignancy of tumour cells may be related to the magnitude of the cell surface charge presented by exposed macromolecular groups of the enlarged muco-polysaccharide layers around tumour cells1, and it has also been suggested2 that this surface charge inhibits the recognition of tumour antigens by lymphocytes. Removal of excess mucopolysaccharide with neuraminidase restores fibroblast cells which are transformed by polyoma virus to normal3. Ehrlich ascites tumour cells, which have a large negative surface charge, provide a sensitive system for electrophoretic studies of some surface properties.

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Author information

Author notes

  1. M. H. REPACHOLI

    Present address: Saskatchewan Cancer Commission, Allan Blair Memorial Clinic, Regina, Saskatchewan

Authors and Affiliations

  1. Department of Physics, Guy's Hospital Medical School, London, SE1

    M. H. REPACHOLI

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  1. M. H. REPACHOLI
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REPACHOLI, M. Electrophoretic Mobility of Tumour Cells exposed to Ultrasound and Ionizing Radiation. Nature 227, 166–167 (1970). https://doi.org/10.1038/227166a0

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