Protein-synthesizing Structures associated with Mitochondria

Abstract

Protein synthesis in HeLa cell mitochondria is associated with a structure sedimenting at 95S. This has some properties in common with bacterial ribosomes but its physicochemical properties are rather different.

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References

  1. 1

    Work, T. S., Coote, J. L., and Ashwell, M., Fed. Proc., 27, 5 (1968).

    Google Scholar 

  2. 2

    Wagner, R., Science, 163, 1026 (1969).

    ADS  CAS  Article  Google Scholar 

  3. 3

    Gibor, A., and Granick, S., Science, 145, 890 (1964).

    ADS  CAS  Article  Google Scholar 

  4. 4

    Roodyn, D. B., and Wilkie, D., The Biogenesis of Mitochondria (Methuen, London, 1968).

    Google Scholar 

  5. 5

    Nass, M. M. K., Science, 165, 25 (1969).

    ADS  CAS  Article  Google Scholar 

  6. 6

    Vesco, C., and Penman, S., Proc. US Nat. Acad. Sci., 62, 218 (1968).

    ADS  Article  Google Scholar 

  7. 7

    Rifkin, M., Wood, D., and Luck, D., Proc. US Nat. Acad. Sci., 58, 1025 (1967).

    ADS  CAS  Article  Google Scholar 

  8. 8

    Kuntzel, H., and Noll, H., Nature, 215, 1340 (1967).

    ADS  CAS  Article  Google Scholar 

  9. 9

    Dure, L., Epler, J., and Barnett, W., Proc. US Nat. Acad. Sci., 58, 1883 (1967).

    ADS  CAS  Article  Google Scholar 

  10. 10

    Rogers, P., Preston, B., Titchener, E., and Linnane, A., Biochem. Biophys. Res. Commun., 27, 405 (1967).

    CAS  Article  Google Scholar 

  11. 11

    Leon, S., and Mahler, H., Arch. Biochem. Biophys., 126, 305 (1968).

    CAS  Article  Google Scholar 

  12. 12

    Dubin, D., and Brown, R., Biochim. Biophys. Acta, 145, 538 (1967).

    CAS  Article  Google Scholar 

  13. 13

    Dawid, I., Fed. Proc., 28, 349 (1969).

    Google Scholar 

  14. 14

    Vignais, P., Huet, J., and Andre, J., FEBS Letters, 3, 177 (1969).

    CAS  Article  Google Scholar 

  15. 15

    Kuntzel, H., Nature, 222, 142 (1969).

    ADS  CAS  Article  Google Scholar 

  16. 16

    Linnane, A., and Firkin, F., Biochem. Biophys. Res. Commun., 32, 398 (1968).

    Article  Google Scholar 

  17. 17

    Rabinowitz, H., De Salle, L., Sinclair, J., Stirewalt, R., and Swift, H., Fed. Proc., 25, 581 (1966).

    Google Scholar 

  18. 18

    Kalf, G., Arch. Biochem. Biophys., 101, 350 (1963).

    CAS  Article  Google Scholar 

  19. 19

    Kroon, A., Biochim. Biophys. Acta, 108, 275 (1965).

    CAS  Article  Google Scholar 

  20. 20

    Kroon, A., Biochim. Biophys. Acta, 72, 391 (1963).

    CAS  Article  Google Scholar 

  21. 21

    Godchaux, W., and Herbert, E., J. Mol. Biol., 21, 537 (1966).

    CAS  Article  Google Scholar 

  22. 22

    Beattie, D., Basford, R., and Koritz, S., Biochemistry, 6, 3099 (1967).

    CAS  Article  Google Scholar 

  23. 23

    O'Brien, T., and Kalf, G., J. Biol. Chem., 242, 2172, 2180 (1967).

    CAS  PubMed  Google Scholar 

  24. 24

    Loeb, J., and Hubby, B., Biochim. Biophys. Acta, 166, 745 (1968).

    CAS  Article  Google Scholar 

  25. 25

    Eagle, H., Science, 130, 432 (1959).

    ADS  CAS  Article  Google Scholar 

  26. 26

    Zylber, E., Vesco, C., and Penman, S., J. Mol. Biol., 44, 195 (1969).

    CAS  Article  Google Scholar 

  27. 27

    Attardi, B., Cravioto, B., and Attardi, G., J. Mol. Biol., 44, 47 (1969).

    CAS  Article  Google Scholar 

  28. 28

    Lamb, A., Clark-Walker, G., and Linnane, A., Biochim. Biophys. Acta, 161, 415 (1968).

    CAS  Article  Google Scholar 

  29. 29

    Sebald, W., Bucher, T., Olbrick, B., and Kaudewitz, F., FEBS Letters, 1, 235 (1968).

    CAS  Article  Google Scholar 

  30. 30

    Salzman, N., Lockart, jun., R., and Sebring, E., Virology, 9, 244 (1959).

    CAS  Article  Google Scholar 

  31. 31

    Darnell, J., and Levintow, L., J. Biol. Chem., 235, 74 (1960).

    CAS  PubMed  Google Scholar 

  32. 32

    Zimmerman, E., Heeter, M., and Darnell, J., Virology, 19, 400 (1963).

    CAS  Article  Google Scholar 

  33. 33

    Holland, J., and Peterson, J., J. Mol. Biol., 8, 556 (1964).

    CAS  Article  Google Scholar 

  34. 34

    Penman, S., Scherrer, K., Becker, Y., and Darnell, J., Proc. US Nat. Acad. Sci., 49, 654 (1963).

    ADS  CAS  Article  Google Scholar 

  35. 35

    Holland, J., J. Mol. Biol., 8, 574 (1964).

    CAS  Article  Google Scholar 

  36. 36

    Bablanian, R., Eggers, H., and Tamm, I., Virology, 26, 100 (1965).

    CAS  Article  Google Scholar 

  37. 37

    Penman, S., and Summers, D., Virology, 27, 614 (1965).

    CAS  Article  Google Scholar 

  38. 38

    Perry, R., Exptl. Cell. Res., 29, 400 (1963).

    CAS  Article  Google Scholar 

  39. 39

    Roberts, V., and Newman, J., J. Mol. Biol., 20, 63 (1966).

    CAS  Article  Google Scholar 

  40. 40

    Penman, S., Vesco, C., and Penman, M., J. Mol. Biol., 34, 49 (1968).

    CAS  Article  Google Scholar 

  41. 41

    Warner, J., Knopf, P., and Rich, A., Proc. US Nat. Acad. Sci., 49, 122 (1963).

    ADS  CAS  Article  Google Scholar 

  42. 42

    Gilbert, W., J. Mol. Biol., 6, 389 (1963).

    CAS  Article  Google Scholar 

  43. 43

    Baltimore, D., and Huang, A., Science, 162, 572 (1968).

    ADS  CAS  Article  Google Scholar 

  44. 44

    Perry, R., and Kelly, D., J. Mol. Biol., 16, 255 (1966).

    CAS  Article  Google Scholar 

  45. 45

    Henshaw, E., J. Mol. Biol., 36, 401 (1968).

    CAS  Article  Google Scholar 

  46. 46

    Spirin, A., Belitsina, A., and Lerman, M., J. Mol. Biol., 14, 611 (1965).

    CAS  Article  Google Scholar 

  47. 47

    Girard, M., Latham, H., Penman, S., and Darnell, J., J. Mol. Biol., 11, 187 (1965).

    CAS  Article  Google Scholar 

Download references

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PERLMAN, S., PENMAN, S. Protein-synthesizing Structures associated with Mitochondria. Nature 227, 133–137 (1970). https://doi.org/10.1038/227133a0

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