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Specificity in Bacterial Protein Synthesis : Role of Initiation Factors and Ribosomal Subunits

Abstract

Ribosomes from E. coli initiate synthesis in vitro of all three of the proteins coded by phage f2, but ribosomes from B. stearothermophilus initiate synthesis of only one. The specificity of initiation depends only on the source of the 30S subunits; the origin of the 50S sub-units and initiation factors has no effect.

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LODISH, H. Specificity in Bacterial Protein Synthesis : Role of Initiation Factors and Ribosomal Subunits. Nature 226, 705–707 (1970). https://doi.org/10.1038/226705a0

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