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Inhibition by Hapten of Cellular Immune Responses to a Hapten–Protein Conjugate

Nature volume 226, pages 173–174 (1970)Cite this article

Abstract

STIMULATION of specific immunocompetent cells by antigen has been postulated to involve an interaction of antigen with a complementary cell surface receptor. Furthermore, the specificity of these receptors, although not precisely established, may be very similar to that of serum-type antibody1–3. Evidence for this, in the case of anamnestic antihapten–protein antibody responses, has been obtained by studying the capacity of haptens to inhibit stimulation of secondary responses to hapten–protein conjugates1,4,5.

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Authors and Affiliations

  1. Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20014

    THOMAS C. FRANCIS & WILLIAM E. PAUL

Authors
  1. THOMAS C. FRANCIS
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  2. WILLIAM E. PAUL
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FRANCIS, T., PAUL, W. Inhibition by Hapten of Cellular Immune Responses to a Hapten–Protein Conjugate. Nature 226, 173–174 (1970). https://doi.org/10.1038/226173a0

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  • DOI: https://doi.org/10.1038/226173a0

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