Abstract
THE commercial availability of zonal rotors and centrifuges within the past 3–4 years has permitted the exploitation of zonal centrifugation for large scale fractionation of cellular components. In particular, attention has been focused on the isolation of relatively large components such as cell organelles and sub-fractions, viruses and RNA, although the technique has also been applied to enzyme purification1.
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References
Setlow, B., and Lowenstein, J. M., J. Biol. Chem., 242, 607 (1967).
Self, C. H., and Weitzman, P. D. J., Abst. of the Sixth FEBS Meeting, Madrid, No. 249 (1969).
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SELF, C., WEITZMAN, P. Separation of Isoenzymes by Zonal Centrifugation. Nature 225, 644–645 (1970). https://doi.org/10.1038/225644a0
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DOI: https://doi.org/10.1038/225644a0
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