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New Approach to Cancer

Abstract

A unified theory of growth, cytodifferentiation and disease can explain many features of natural cancers which are incompatible with purely cytological explanations.

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References

  1. Smithers, D. W., Lancet, i, 443 (1962).

  2. Burch, P. R. J., and Burwell, R. G., Quart. Rev. Biol., 40, 252 (1965).

    Article  Google Scholar 

  3. Burch, P. R. J., An Inquiry Concerning Growth, Disease and Ageing (Oliver and Boyd, Edinburgh, 1968; University of Toronto Press, Buffalo, New York, 1969).

    Google Scholar 

  4. Burch, P. R. J., and Rowell, N. R., Acta Derm.-venereol. Stock., 45, 366 (1965); 48, 33 (1968).

    CAS  Google Scholar 

  5. Burch, P. R. J., and Milunsky, A., Lancet, i, 554 (1969).

  6. Burch, P. R. J., de Dombal, F. T., and Watkinson, G., Gut, 10, 277 (1969).

    Article  CAS  Google Scholar 

  7. Jackson, D., and Burch, P. R. J., Gerontologia, 15, 203 (1969).

    Article  CAS  Google Scholar 

  8. Burnet, F. M., The Clonal Selection Theory of Acquired Immunity (Cambridge University Press, London, 1959).

    Book  Google Scholar 

  9. Burnet, F. M., Brit. Med. J., 1, 338 (1965); Lancet, i, 1383 (1968); Burnet, F. M., and Holmes, M. C., Nature, 207, 368 (1965).

    Article  CAS  Google Scholar 

  10. Burch, P. R. J., in Radiation-Induced Cancer, 29 (Proceedings Series, International Atomic Energy Agency, Vienna, 1969).

    Google Scholar 

  11. Billingham, R. E., and Silvers, W. K., New Engl. J. Med., 268, 477 (1963).

    Article  Google Scholar 

  12. Billingham, R. E., and Silvers, W. K., J. Exp. Med., 125, 429 (1967).

    Article  CAS  Google Scholar 

  13. Boyse, E. A., Stockert, E., and Old, L. J., Proc. US Nat. Acad. Sci., 58, 954 (1967).

    Article  ADS  CAS  Google Scholar 

  14. de Dombal, F. T., Gut, 9, 144 (1968).

    Article  CAS  Google Scholar 

  15. Jackson, D., Proc. Roy. Soc. Med., 61, 265 (1968).

    CAS  PubMed  Google Scholar 

  16. Smithers, D. W., A Clinical Prospect of the Cancer Problem (Livingstone, Edinburgh and London, 1960).

    Google Scholar 

  17. Willis, R. S., Pathology of Tumours, third ed. (Butterworth, London, 1960).

    Google Scholar 

  18. Lynch, H. T., Hereditary Factors in Carcinomas (Springer-Verlag, Berlin, Heidelberg, New York, 1967).

    Book  Google Scholar 

  19. Johnson, L. D., Nickerson, R. J., Easterday, C. L., Stuart, R. S., and Hertig, A. T., Cancer, 22, 901 (1968).

    Article  CAS  Google Scholar 

  20. Ashley, D. J. B., and Davies, H. D., Gut, 7, 542 (1966).

    Article  CAS  Google Scholar 

  21. Laird, A. K., Brit. J. Cancer, 18, 490 (1964).

    Article  Google Scholar 

  22. Laird, A. K., Brit. J. Cancer, 19, 278 (1965).

    Article  CAS  Google Scholar 

  23. Billingham, R. E., Orr, J. W., and Woodhouse, D. L., Brit. J. Cancer, 5, 417 (1951).

    Article  CAS  Google Scholar 

  24. Marchant, J., and Orr, J. W., Brit. J. Cancer, 7, 329 (1953).

    Article  CAS  Google Scholar 

  25. Orr, J. W., Brit. Med. Bull., 14, 99 (1968).

    Article  Google Scholar 

  26. Bond, B., and Orr, J. W., Brit. J. Cancer, 23, 188 (1969).

    Article  CAS  Google Scholar 

  27. Arundell, F. D., Karasek, M. A., and Gates, A. H., J. Invest. Dermatol., 52, 119 (1969).

    Article  CAS  Google Scholar 

  28. Tarin, D., Brit. J. Cancer, 23, 417 (1969).

    Article  CAS  Google Scholar 

  29. Bond, V. P., Shellabarger, C. J., Cronkite, E. P., and Fliedner, T. M., Radiat. Res., 13, 318 (1960).

    Article  ADS  CAS  Google Scholar 

  30. Burns, F. J., Albert, R. E., and Heimbach, R. D., Radiat. Res., 36, 225 (1968).

    Article  ADS  CAS  Google Scholar 

  31. Hulse, E. V., Mole, R. H., and Papworth, D. G., Intern. J. Radiat. Biol., 14, 437 (1968).

    CAS  Google Scholar 

  32. Barendsen, G. W., in Radiation-Induced Cancer, 413 (Proceedings Series, International Atomic Energy Agency, Vienna, 1969).

    Google Scholar 

  33. Glucksmann, A., in Cellular Basis and Aetiology of Late Somatic Effects of Ionizing Radiation (edit. by Harris, B. J. C.), 121 (Academic Press, London, 1963).

    Google Scholar 

  34. Albert, R. E., Burns, F. J., and Heimbach, R. D., Radiat. Res., 30, 515 (1967).

    Article  ADS  CAS  Google Scholar 

  35. Heimbach, R. D., Burns, F. J., and Albert, R. E., Radiat. Res., 39, 332 (1969).

    Article  ADS  CAS  Google Scholar 

  36. Riley, J. F., Experientia, 24, 1237 (1968).

    Article  CAS  Google Scholar 

  37. Riley, J. F., Lancet, ii, 1457 (1966).

  38. Todaro, G. J., and Green, H., Proc. US Nat. Acad. Sci., 55, 302 (1966).

    Article  ADS  CAS  Google Scholar 

  39. Borek, C., and Sachs, L., Proc. US Nat. Acad. Sci., 59, 83 (1968).

    Article  ADS  CAS  Google Scholar 

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BURCH, P. New Approach to Cancer. Nature 225, 512–516 (1970). https://doi.org/10.1038/225512a0

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  • DOI: https://doi.org/10.1038/225512a0

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