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Relation of Regenerating Nerve Terminals to Original Endplates

Abstract

USING silver impregnation Tello and Gutmann1 and Young2 examined the process of denervation and re-innervation of skeletal muscle endplates after injury of the motor nerve, and found that the regenerated nerves terminated in the regions of the original endplates. Several experiments on nerve implantation were subsequently reported which demonstrated the possibility of the formation of new endplates3–7. Several electron microscopic studies have recently been conducted on degenerating endplates and have indicated the persistence of secondary synaptic clefts after degeneration in mammalian skeletal muscles8,9.

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IWAYAMA, T. Relation of Regenerating Nerve Terminals to Original Endplates. Nature 224, 81–82 (1969). https://doi.org/10.1038/224081a0

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