Mycophenolic Acid: an Anti-cancer Compound with Unusual Properties


MYCOPHENOLIC acid (UK patent applications 43131/66 and 43132/66) emerged as a potential anti-cancer compound during routine screening tests with mould filtrates for activity against mouse fibroblasts. Our aim was to detect substances having a more specific action than general lethality: substances which, for example, inhibit cell division or interfere with the mitotic mechanism.

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CARTER, S., FRANKLIN, T., JONES, D. et al. Mycophenolic Acid: an Anti-cancer Compound with Unusual Properties. Nature 223, 848–850 (1969).

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