Abstract
WE report here the synthesis of substances, structurally related to the prostaglandins, capable of selectively antagonizing the smooth muscle effects of both prostaglandins E1 and F1α. The availability of specific antagonists of prostaglaiidin may help solve problems about the physiological roles of the prostaglandins1.
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References
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FRIED, J., SANTHANAKRISHNAN, T., HIMIZU, J. et al. Prostaglandin Antagonists: Synthesis and Smooth Muscle Activity. Nature 223, 208–210 (1969). https://doi.org/10.1038/223208a0
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DOI: https://doi.org/10.1038/223208a0
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