Abstract
Hardy and Ling pointed out that irradiated lymphoma cells markedly activate human lymphocytes in a mixed cell reaction in vitro1. As a radiotherapist concerned in the day to day care of lymphoma patients, this information suggests to me the first rational explanation of a phenomenon frequently observed in this group of diseases. I refer to the situation where irradiation of a group of lymphomatous glands, with a single small dose, results in rapid clinical regression of other lymphomatous masses at distant sites in the body.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Hardy, D. A., and Ling, N. R., Nature, 221, 545 (1969).
Spangler, G., and Cassen, B., Radiat. Res., 30, 22 (1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
RYALL, R. Effects of Some Cellular Antigens on Lymphocytes and the Nature of the Mixed Lymphocyte Reaction. Nature 223, 196–197 (1969). https://doi.org/10.1038/223196a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/223196a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
