Abstract
THERE is reason to believe that the site at which antigen is recognized is located on a precursor of the antibody producing cell; it is thought to have antigen binding properties similar or identical to the antigen binding site of the antibody which that cell will produce if appropriately stimulated1,2. Antigens can bind to the surface of antibody producing cells3,4; and immunoglobulin molecules have been detected on the surface of lymphocytes5.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Mitchison, N. A., Symp. Int. Soc. Cell Biol., 7, 29 (1968).
Goidl, E. A., Paul, W. E., Siskind, G. W., and Benacerraf, B., J. Immunol., 100, 371 (1968).
Wigzell, H., and Andersson, B., J. Exp. Med., 129, 23 (1969).
Reiss, E., Mertens, E., and Enrich, W. E., Proc. Soc. Exp. Biol., NY, 74, 732 (1950).
Sell, S., and Gell, P. G. H., J. Exp. Med., 122, 423 (1965).
Wofsy, L., Metzger, H., and Singer, S. J., Biochemistry, 1, 1031 (1962).
Brownstone, A., Mitchison, N. A., and Pitt-Rivers, R., Immunology, 10, 465 (1966).
Brownstone, A., Mitchison, N. A., and Pitt-Rivers, R., Immunology, 10, 481 (1966).
Mitchison, N. A., Cold Spring Harbor Symp. Quant. Biol., 32, 431 (1967).
Good, A. H., Traylor, P. S., and Singer, S. J., Biochemistry, 6, 873 (1967).
Britton, S., J. Exp. Med., 129, 469 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PLOTZ, P. Specific Inhibition of an Antibody Response by Affinity Labelling. Nature 223, 1373–1374 (1969). https://doi.org/10.1038/2231373a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/2231373a0
This article is cited by
-
Reversible Blocking Effect of Anti-mouse Immunoglobulin Serum on the Induction of Immunity and Tolerance in vitro
Nature New Biology (1971)
-
Mathematical Model of Clonal Selection and Antibody Production
Nature (1970)
-
Inhibition by Hapten of Cellular Immune Responses to a Hapten–Protein Conjugate
Nature (1970)
-
Tolerance Induction by an Apparently Non-immunogenic Molecule
Nature (1970)
-
Membranaspekte der Immunologie
Die Naturwissenschaften (1970)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.