Abstract
IN all eukaryotic organisms so far investigated, the genomic DNA includes reiterated DNA sequences which are referred to as families of related base sequences1, and two molecular models of chromosome structure which have recently been put forward are consistent with these observations. Callan7's master–slave hypothesis2 has it that certain regions of the chromosomal DNA, especially those of the lateral loops of lampbrush chromosomes, are sequential reiterations of functionally equivalent gene sequences. Similarly, Beermann3 has proposed that the chromomere of the chromosome is a repository for families of similar but not necessarily identical genes. These models account for many cytogenetic, genetic and ultrastructural phenomena.
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BIRNSTIEL, M., GRUNSTEIN, M., SPEIRS, J. et al. Family of Ribosomal Genes of Xenopus laevis. Nature 223, 1265–1267 (1969). https://doi.org/10.1038/2231265a0
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DOI: https://doi.org/10.1038/2231265a0
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