Letter | Published:

Substructures in Ribosomes of E. coli ? A Hypothesis for the Attachment of Transfer RNAs

Nature volume 222, pages 979981 (07 June 1969) | Download Citation

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Abstract

RECENT structural models1 for ribosomes give no insight into the interaction between ribosomal components and tRNA and mRNA during translation. We propose a structural model for the E. coli ribosome which does this through substructures, consisting of protein and RNA, which are spatially organized in the 70S ribosome and direct individual tRNAs to a common peptide bond formation site.

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Affiliations

  1. Laboratory for Physiological Chemistry, State University of Leiden, The Netherlands.

    • WIM MöLLER

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DOI

https://doi.org/10.1038/222979a0

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