Article | Published:

New Unstable Haemoglobin Borås: β88 (F4) Leucine→Arginine

Nature volume 222, pages 953955 (07 June 1969) | Download Citation

Subjects

Abstract

Haemoglobin Borås has a mutation in which arginine is substituted for leucine in the haem pocket. The introduction of a positive charge into the haem pocket is probably avoided by the accommodation of the guanidinium group in an external crevice of the molecule.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , , , , and , Nature, 215, 626 (1967).

  2. 2.

    , and , Scand. J. Haematol., 4, 241 (1967).

  3. 3.

    , , and , J. Med. Genet., 5, 292 (1968).

  4. 4.

    , , , , , , and , Brit. J. Haematol., 10, 388 (1964).

  5. 5.

    , Cold Spring Harbor Symp. Quant. Biol., 29, 297 (1964).

  6. 6.

    , and , J. Mol. Biol., 19, 91 (1966).

  7. 7.

    , , and , Scand. J. Haematol., 5, 353 (1968).

  8. 8.

    , , , and , Nature, 219, 131 (1968).

  9. 9.

    , and , Biochim. Biophys. Acta, 50, 595 (1961).

  10. 10.

    , and , Nature, 219, 902 (1968).

  11. 11.

    , and , Proc. US Nat. Acad. Sci., 47, 1758 (1961).

  12. 12.

    , and , Nature, 190, 663 (1961).

Download references

Author information

Affiliations

  1. Department of Clinical Chemistry, Lidköping, Sweden

    • A. HOLLENDER
  2. MRC Abnormal Haemoglobin Unit, University Department of Biochemistry, Cambridge

    • P. A. LORKIN
    •  & H. LEHMANN
  3. Department of Geriatrics and Rehabilitation, Skara, Sweden

    • B. SVENSSON

Authors

  1. Search for A. HOLLENDER in:

  2. Search for P. A. LORKIN in:

  3. Search for H. LEHMANN in:

  4. Search for B. SVENSSON in:

About this article

Publication history

Received

Published

DOI

https://doi.org/10.1038/222953a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.