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Cone Dominance of the Human Early Receptor Potential

Nature volume 222, pages 12721273 (28 June 1969) | Download Citation

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Abstract

THE early receptor potential (ERP) of the frog and monkey retinas is generated chiefly by cone visual pigments, even though the predominant visual pigment in these retinas is rhodopsin1,2. Rhodopsin, however, is responsible for the large ERP of the rod-dominated rat retina3. The purpose of the experiments reported here was to determine whether the ERP of the rod-dominated human retina is generated primarily by cone pigments or by rhodopsin. The rate of ERP recovery after a bleaching flash was compared with the rates of rod and cone dark adaptation measured psychophysically after the same bleaching flash.

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Author information

Author notes

    • E. BRUCE GOLDSTEIN

    Address after August 1, 1969: Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.

Affiliations

  1. Biological Laboratories, Harvard University, Cambridge, Massachusetts 02138.

    • E. BRUCE GOLDSTEIN
  2. Department of Ophthalmology, Harvard Medical School, 300 Longwood Avenue, Boston, Massachusetts 02115.

    • ELIOT L. BERSON

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https://doi.org/10.1038/2221272a0

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