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Mechanism of Synthesis of Bacteriophage RNA

Nature volume 222, pages 121–123 (1969)Cite this article

Abstract

Several steps in the in vitro synthesis of infectious bacteriophage RNA and the properties of some components of the system can now be described. The mechanism of this reaction seems to be considerably more complex than was proposed in earlier models.

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References

  1. Haruna, I., Nozu, K., and Spiegelman, S., Proc. US Nat. Acad. Sci., 50, 905 (1963).

    Article  ADS  CAS  Google Scholar 

  2. Weissmann, C., Simon, L., and Ochoa, S., Proc. US Nat. Acad. Sci., 49, 407 (1963).

    Article  ADS  CAS  Google Scholar 

  3. August, J. T., Cooper, S., Shapiro, L., and Zinder, N. D., Cold Spring Harbor Symp. Quant. Biol., 28, 95 (1963).

    Article  CAS  Google Scholar 

  4. Eoyang, L., and August, J. T., in Methods in Enzymology (edit. by Colowick, S. P., and Kaplan, N. O.) 12B, 530 (Academic Press, New York, 1968).

    Google Scholar 

  5. Pace, N. R., Haruna, I., and Spiegelman, S., in Methods in Enzymology (edit. by Colowick, S. P., and Kaplan, N. O.), 12B, 540 (Academic Press, New York, 1968).

    Google Scholar 

  6. Spiegelman, S., Haruna, I., Holland, I. B., Beaudreau, G., and Mills, D., Proc. US Nat. Acad. Sci., 54, 949 (1965).

    Article  ADS  Google Scholar 

  7. Lodish, H. F., and Zinder, N. D., Science, 152, 372 (1966).

    Article  ADS  CAS  Google Scholar 

  8. Eikhom, T. S., and Spiegelman, S., Proc. US Nat. Acad. Sci., 57, 1833 (1967).

    Article  ADS  CAS  Google Scholar 

  9. Eikhom, T. S., Stockley, D. J., and Spiegelman, S., Proc. US Nat. Acad. Sci., 59, 506 (1968).

    Article  ADS  CAS  Google Scholar 

  10. Haruna, I., and Spiegelman, S., Proc. US Nat. Acad. Sci., 54, 579 (1965).

    Article  ADS  CAS  Google Scholar 

  11. Feix, G., Pollet, R., and Weissmann, C., Proc. US Nat. Acad. Sci., 59, 145 (1968).

    Article  ADS  CAS  Google Scholar 

  12. Mills, D., Peterson, R. L., and Spiegelman, S., Proc. US Nat. Acad. Sci., 58, 217 (1967).

    Article  ADS  CAS  Google Scholar 

  13. Banerjee, A. K., Rensing, U., and August, J. T., Proc. US Nat. Acad. Sci. (in the press).

  14. Hori, K., Eoyang, L., Banerjee, A. K., and August, J. T., Proc. US Nat Acad. Sci., 57, 1790 (1967).

    Article  ADS  CAS  Google Scholar 

  15. Banerjee, A. K., Eoyang, L., Hori, K., and August, J. T., Proc. US Nat. Acad. Sci., 57, 986 (1967).

    Article  ADS  CAS  Google Scholar 

  16. Watanabe, M., and August, J. T., Proc. US Nat. Acad. Sci., 59, 513 (1968).

    Article  ADS  CAS  Google Scholar 

  17. Roblin, R., J. Mol. Biol., 31, 51 (1968).

    Article  CAS  Google Scholar 

  18. DeWachter, R., Verhassel, J-P., and Fiers, W., FEBS Lett., 1, 93 (1968).

    Article  CAS  Google Scholar 

  19. Glitz, D., Biochemistry, 7, 927 (1968).

    Article  CAS  Google Scholar 

  20. Dahlberg, J. E., Nature, 220, 548 (1968).

    Article  ADS  CAS  Google Scholar 

  21. DeWachter, R., and Fiers, W., Nature, 221, 233 (1969).

    Article  ADS  CAS  Google Scholar 

  22. Bishop, D. H. L., Mills, D. R., and Spiegelman, S., Biochemistry, 7, 3744 (1968).

    Article  CAS  Google Scholar 

  23. Weith, H. L., and Gilham, P. T., J. Amer. Chem. Soc., 89, 5473 (1967).

    Article  CAS  Google Scholar 

  24. DeWachter, R., and Fiers, W., J. Mol. Biol., 30, 507 (1967).

    Article  CAS  Google Scholar 

  25. August, J. T., Banerjee, A. K., Eoyang, L., Franze de Fernandez, M. T., Hasegawa, S., Hori, K., Kuo, C. H., Rensing, U., and Shapiro, L., Cold Spring Harbor Symp. Quant. Biol., Vol. 33 (1968).

  26. Franze de Fernandez, M. T., Eoyang, L., and August, J. T., Nature, 219, 588 (1968).

    Article  ADS  CAS  Google Scholar 

  27. Shapiro, L., Franze de Fernandez, M. T., and August, J. T., Nature, 220, 478 (1968).

    Article  ADS  CAS  Google Scholar 

  28. Weissmann, C., and Feix, G., Proc. US Nat. Acad. Sci., 55, 1264 (1966).

    Article  ADS  CAS  Google Scholar 

  29. Bishop, D. H. L., Pace, N. R., and Spiegelman, S., Proc. US Nat. Acad. Sci., 58, 1790 (1967).

    Article  ADS  CAS  Google Scholar 

  30. Kamen, R., Nature, 221, 321 (1969).

    Article  ADS  CAS  Google Scholar 

  31. Feix, G., Slor, H., and Weissmann, C., Proc. US Nat. Acad. Sci., 57, 1401 (1967).

    Article  ADS  CAS  Google Scholar 

  32. Robertson, H. D., Webster, R. E., and Zinder, N. D., J. Biol. Chem., 243, 82 (1968).

    CAS  Google Scholar 

  33. Weissmann, C., Feix, G., Slor, H., and Pollet, R., Proc. US Nat. Acad. Sci., 57, 1870 (1967).

    Article  ADS  CAS  Google Scholar 

  34. Francke, B., and Hofschneider, P. H., J. Mol. Biol., 16, 544 (1966).

    Article  CAS  Google Scholar 

  35. Franklin, R. M., Proc. US Nat. Acad. Sci., 55, 1504 (1966).

    Article  ADS  CAS  Google Scholar 

  36. Feix, G., Pollet, R., and Weissmann, C., Proc. US Nat. Acad. Sci., 59, 145 (1968).

    Article  ADS  CAS  Google Scholar 

  37. Mills, D. R., Pace, N. R., and Spiegelman, S., Proc. US Nat. Acad. Sci., 56, 1778 (1966).

    Article  ADS  CAS  Google Scholar 

  38. Klee, C. B., and Singer, M. F., J. Biol. Chem., 243, 923 (1968).

    PubMed  CAS  Google Scholar 

  39. Nossal, N. G., and Singer, M. F., J. Biol. Chem., 243, 913 (1968).

    PubMed  CAS  Google Scholar 

  40. Lazarus, H. M., Sporn, M. B., and Bradley, D. F., Proc. US Nat. Acad. Sci., 60, 1503 (1968).

    Article  ADS  CAS  Google Scholar 

  41. Iglewski, W. T., and Franklin, R. M., Proc. US Nat. Acad. Sci., 58, 1018 (1967).

    Article  ADS  Google Scholar 

  42. Pollet, R., Knolle, P., and Weissmann, C., Proc. US Nat. Acad. Sci., 58, 766 (1967).

    Article  ADS  CAS  Google Scholar 

  43. Robertson, H. D., and Zinder, N. D., Nature, 220, 69 (1968).

    Article  ADS  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Molecular Biology, Division of Biological Sciences, Albert Einstein College of Medicine, Bronx, New York, 10461

    J. THOMAS AUGUST

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  1. J. THOMAS AUGUST
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AUGUST, J. Mechanism of Synthesis of Bacteriophage RNA. Nature 222, 121–123 (1969). https://doi.org/10.1038/222121a0

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