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Mechanism of the Action of Taste-modifying Protein

Abstract

THE “taste-modifying protein” that has been isolated from miracle fruit (Synsepalum dulcificum)1 is a basic glycoprotein with a probable molecular weight of 44,000. Applied to the tongue it modifies taste so that sour substances taste sweet. Brouwer et al.2 have isolated a similar protein from miracle fruit. We describe here a psychological study of the protein designed to clarify its mechanism of action.

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References

  1. Kurihara, K., and Beidler, L. M., Science, 161, 1241 (1968).

    Article  ADS  CAS  Google Scholar 

  2. Brouwer, J. N., Van Der Weil, H., Francke, A., and Henning, G. J., Nature, 220, 373 (1968).

    Article  ADS  CAS  Google Scholar 

  3. Beidler, L. M., Olfaction and Taste II, 509 (1967).

  4. Harris, H., and Kalmus, H., Ann. Eugen. (London), 15, 24 (1949).

    Article  CAS  Google Scholar 

  5. Fischer, R., Griffin, F., and Kaplan, A. R., Med. Exp., 9, 151 (1963).

    CAS  Google Scholar 

  6. Warren, R. M., and Pfaffmann, C., J. Appl. Physiol., 14, 40 (1959).

    Article  CAS  Google Scholar 

  7. Stöcklin, W., Helv. Chim. Acta, 50, 491 (1967).

    Article  Google Scholar 

  8. Stöcklin, W., Weiss, E., and Reichstein, T., Helv. Chim. Acta, 50, 474 (1967).

    Article  Google Scholar 

  9. Monod, J., Changeux, J. P., and Jacob, F., J. Mol. Biol., 6, 306 (1963).

    Article  CAS  Google Scholar 

  10. Scheraga, H. A., Protein Structure (Academic Press, London and New York, 1961).

    Google Scholar 

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KURIHARA, K., BEIDLER, L. Mechanism of the Action of Taste-modifying Protein. Nature 222, 1176–1179 (1969). https://doi.org/10.1038/2221176a0

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