Abstract
DEMYELINATION is an important pathological process affecting nerve fibres. It is characterized histologically by destruction of the myelin sheath with preservation of axis cylinder continuity. The process affects peripheral nerves in various forms of polyneuritis, and the central nervous system in multiple (disseminated) sclerosis. The effects of demyelination on conduction in the peripheral nervous system are now well established1, but little is known of the way in which conduction in the central nervous system is affected by myelin damage.
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MCDONALD, W., SEARS, T. Effect of Demyelination on Conduction in the Central Nervous System. Nature 221, 182–183 (1969). https://doi.org/10.1038/221182a0
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DOI: https://doi.org/10.1038/221182a0
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