Abstract
The following two articles present a way of determining the chirality of doubly labelled methyl groups, and reveal that the condensation reaction catalysed by malate synthase takes place with inversion of configuration.
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References
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For review of evidence see Progress in Stereochemistry (edit. by Klyne, W.), 187 (Butterworths, London, 1954).
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CORNFORTH, J., REDMOND, J., EGGERER, H. et al. Asymmetric Methyl Groups: Asymmetric Methyl Groups, and the Mechanism of Malate Synthase. Nature 221, 1212–1213 (1969). https://doi.org/10.1038/2211212a0
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DOI: https://doi.org/10.1038/2211212a0
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