Light Stimulation of the Sodium Pump in Epithelia


WHEN pieces of isolated skin are exposed to intense flashes of light lasting less than 1 ms, an electrical response can be detected between electrodes placed on the two sides1. This consists of a 1 ms initial response during which the anatomical inside surface of the skin is negative, followed by a slower series of waves of varying polarity but dominated by a component with a peak latency of usually 10–20 ms, positive inside (Fig. 1, +70 mV). In the previous report1, this complex was termed the early response to distinguish it from a later response, a much slower transient alteration in potential lasting several seconds that was observed in frog skin. Both the early and late responses increase linearly with stimulus energy.

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BECKER, H., GOLDSMITH, T. Light Stimulation of the Sodium Pump in Epithelia. Nature 220, 1236–1239 (1968).

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