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Polychlorinated Biphenyls in the Global Ecosystem

Abstract

Polychlorinated biphenyls are widely dispersed in the global ecosystem, and are powerful inducers of hepatic enzymes which degrade oestradiol. Together with other chlorinated biocides, such as DDT, they could account for a large part of the aberration in calcium metabolism which has been observed in many species of birds since the Second World War.

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References

  1. Ratcliffe, D. A., Nature, 215, 208 (1967).

    Article  ADS  CAS  Google Scholar 

  2. Hickey, J. J., and Anderson, D. W., Science, 162, 271 (1968).

    Article  ADS  CAS  Google Scholar 

  3. Risebrough, R. W., in Chemical Fallout, First Rochester Conference on Toxicity (in the press, 1968).

    Google Scholar 

  4. Simkiss, K., Calcium in Reproductive Physiology (Reinhold, New York, 1967).

    Google Scholar 

  5. Simkiss, K., Biol. Rev., 36, 321 (1961).

    Article  CAS  Google Scholar 

  6. Clavert, J., and Benoit, J., CR Soc. Biol, Paris, 136, 509 (1942).

    CAS  Google Scholar 

  7. Kyes, P., and Potter, T. S., Anat. Rec., 60, 377 (1934).

    Article  Google Scholar 

  8. Hart, E. B., Steenbock, H., Lepkovsky, S., Kletzien, S. W. F., Halpin, J. G., and Johnson, O. N., J. Biol. Chem., 65, 579 (1925).

    CAS  Google Scholar 

  9. Welch, R. M., Levin, W., and Conney, A. H., Chemical Fallout, First Rochester Conference on Toxicity (in the press).

  10. Hart, L. G., Schultice, R. W., and Fouts, J. R., Toxicol. Appl. Pharmacol., 5, 371 (1963).

    Article  CAS  Google Scholar 

  11. Hart, L. G., and Fouts, J. R., Naunyn-Schmiedeberg's Arch. Exp. Path. Pharmakol., 249, 486 (1965).

    CAS  Google Scholar 

  12. Conney, A. H., Welch, R. M., Kuntzman, R., and Burns, J. J., Clin Pharmacol. Therap., 8, 2 (1966).

    Article  Google Scholar 

  13. Conney, A. H., Pharmacol. Rev., 19, 317 (1967).

    CAS  Google Scholar 

  14. Kupfer, D., Residue Rev., 19, 11 (1967).

    PubMed  CAS  Google Scholar 

  15. Gerboth, G., and Schwabe, U., Arch. Exp. Pathol. Pharmakol., 246, 469 (1964).

    Article  CAS  Google Scholar 

  16. Gillett, J. W., J. Agric. Food Chem., 16, 295 (1968).

    Article  CAS  Google Scholar 

  17. Schwabe, U., Arzneimittel-Forsch., 14, 1265 (1964).

    CAS  Google Scholar 

  18. Peakall, D. B., Nature, 216, 505 (1967).

    Article  ADS  CAS  Google Scholar 

  19. Welch, R. M., Levin, W., and Conney, A. H., Toxicol Appl. Pharmacol. (in the press).

  20. Bitman, J., Cecil, H. C., Harris, S. J., and Fries, G. F., Science, 162, 371 (1968).

    Article  ADS  CAS  Google Scholar 

  21. Ratcliffe, D. A., Brit. Birds, 51, 23 (1958).

    Google Scholar 

  22. Ratcliffe, D. A., Bird Study, 10, 56 (1963).

    Article  Google Scholar 

  23. Ratcliffe, D. A., Bird Study, 12, 66 (1965).

    Article  Google Scholar 

  24. Ratcliffe, D. A., Bird Study, 14, 238 (1967).

    Article  Google Scholar 

  25. Hickey, J. J., Peregrine Falcon Populations: Their Biology and Decline (University of Wisconsin Press, in the press).

  26. Beebe, F. L., Condor, 62, 145 (1960).

    Article  Google Scholar 

  27. Cade, T. J., White, C. M., and Haugh, J. R., Condor, 70, 170 (1968).

    Article  Google Scholar 

  28. Enderson, J. H., and Berger, D. D., Condor, 70, 149 (1968).

    Article  Google Scholar 

  29. Jensen, S., New Sci., 32, 612 (1966).

    Google Scholar 

  30. Widmark, G., J. Assoc. Off. Anal. Chem., 50, 1069 (1967).

    Google Scholar 

  31. Holmes, D. C., Simmons, J. H., and Tatton, J. O'G., Nature, 216, 227 (1967).

    Article  ADS  CAS  Google Scholar 

  32. Erro, F., Bevenue, A., and Beckman, H., Bull. Environ. Cont. Toxicol., 372 (1967).

  33. White, C. M., Auk, 85, 179 (1968).

    Article  Google Scholar 

  34. Jefferies, D. J., and Prestt, I., Brit. Birds, 59, 49 (1966).

    Google Scholar 

  35. Aldrin, Dieldrin, Endrin (A Status Report) (The Shell Chemical Company 1967).

  36. Risebrough, R. W., Hugget, R. J., Griffin, J. J., and Goldberg, E. D., Science, 159, 1233 (1968).

    Article  ADS  CAS  Google Scholar 

  37. Tech. Bull. PL-306 (Monsanto Chemical Company).

  38. Holden, A. V., and Marsden, K., Nature, 216, 1274 (1967).

    Article  ADS  CAS  Google Scholar 

  39. Ghazal, A., Koransky, W., Portig, J., Vohland, H. W., and Klempau, I., Arch. Exp. Pathol. Pharmakol., 249, 1 (1964).

    Article  CAS  Google Scholar 

  40. Jones, R. E., and Leopold, A. S., J. Wildl. Management, 37, 221 (1967).

    Article  Google Scholar 

  41. Mayhew, W. W., J. Wildl. Management, 19, 36 (1955).

    Article  Google Scholar 

  42. Thayer, G. H., Bird Lore, 6, 47 (1904).

    Google Scholar 

Download references

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RISEBROUGH, R., RIECHE, P., PEAKALL, D. et al. Polychlorinated Biphenyls in the Global Ecosystem. Nature 220, 1098–1102 (1968). https://doi.org/10.1038/2201098a0

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