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Radiation Enhancement of SV40 Transformation in 3T3 and Human Cells

Nature volume 219, pages 520–521 (1968)Cite this article

Abstract

RADIATION1 and viruses2 are implicated in carcinogenesis in man and animals. Kaplan3 has shown that in radiation induced leukaemia in C57Bl mice a virus present in the animal's tissues is the causative agent. Radiation can increase an animal's susceptibility to tumour production by a virus. The direct effect of radiation on the susceptibility of individual cells to tumour viruses can be tested in tissue culture.

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Author information

Authors and Affiliations

  1. National Center for Radiological Health, Rockville, Maryland

    EDWARD J. POLLOCK

  2. National Cancer Institute, Bethesda, Maryland

    GEORGE J. TODARO

Authors
  1. EDWARD J. POLLOCK
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  2. GEORGE J. TODARO
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POLLOCK, E., TODARO, G. Radiation Enhancement of SV40 Transformation in 3T3 and Human Cells. Nature 219, 520–521 (1968). https://doi.org/10.1038/219520a0

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  • DOI: https://doi.org/10.1038/219520a0

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