Abstract
AT least six different electrophoretic variants of human serum albumin have been found in man; three migrate more rapidly than normal and three less rapidly1,2. One of these, a rapidly migrating variant, occurs at a frequency of 5–30 per cent in several tribes of North American Indians3. As one aspect of a multidisciplinary study of the Yanomama Indians of southern Venezuela and adjacent parts of Brazil4, sera from 1,111 individuals residing in twenty-five villages were examined for albumin type. Although no example of the rapidly migrating variant which is common in North American Indians was observed, we did note, when testing 75 of 108 persons residing at the village of Borabuk (2° 45′ N. and 62° 05′ W.), four individuals who possess a variant which also migrates more rapidly towards the anode in starch gel electrophoresis than does normal albumin.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Weitkamp, L. R., Shreffler, D. C., Robbins, J. L., Drachmann, O., Adner, P. L., Wieme, R. J., Simon, N. M., Cooke, K. B., Sandor, G., Wuhrmann, F., Braend, M., and Tárnoky, A. L., Acta Genet. Stat. Med., 17, 399 (1967).
Weitkamp, L. R., Robson, E. B., and Shreffler, D. C., Abst. Amer. Soc. Hum. Genet., Toronto, No. 44, 42 (1967).
Melartin, L., and Blumberg, B. S., Science, 153, 1664 (1966).
Arends, T., Brewer, G., Chagnon, N., Gallango, M. L., Gershowitz, H., Layrisse, M., Neel, J. V., Shreffler, D., Tashian, R., and Weitkamp, L., Proc. US Nat. Acad. Sci., 57, 1252 (1967).
Weitkamp, L. R., Rucknagel, D. L., and Gershowitz, H., Amer. J. Hum. Genet., 18, 559 (1966).
Kaarsalo, E., Melartin, L., and Blumberg, B. S., Science, 158, 123 (1967).
Koch-Grünberg, T., in Festschrift Eduard Seler (Strecker und Schröder, Stuttgart, 1922); Vom Roroima Zum Orinoco, 1 (Dietrich Reimer, Berlin, 1917) and 3 (Strecker und Schröder, Stuttgart, 1923).
Rice, A. H., Geograph. J., 71, 113, 209, 345 (1928).
Migliazza, E., Boletim do Museu Paraense Emilio Goeldi, 22, 1 (1964); 25, 1 (1965).
Chagnon, N. A., dissert., Univ. Michigan (1966).
Neel, J. V., and Chagnon, N. A., Proc. US Nat. Acad. Sci. (in the press).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WEITKAMP, L., CHAGNON, N. Albumin Máku: a New Variant of Human Serum Albumin. Nature 217, 759–760 (1968). https://doi.org/10.1038/217759a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/217759a0
This article is cited by
-
In Memoriam
Human Nature (2020)
-
A genetic study of two French Guiana Amerindian populations
Human Genetics (1978)
-
Genetic studies of the Macushi and Wapishana Indians
Human Genetics (1977)
-
Eine humane serumalbuminvariante (Doppelalbumin�mie)
Human Genetics (1971)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.