Abstract
THERE have been many attempts to determine the magnitude of protein reserves or endogenous nitrogen excretion in protein-depleted or starved animals1–5. Previous results, however, have not clearly stated the fractional rate of catabolism of body protein itself, either for a whole body or for an individual organ or tissue. Borsook6,7 presented the metabolic concept as a development of Martin and Robison's concept2 that the cytoplasmic proteins constituting reserve proteins are broken down at a rate depending on their mass, or in a first-order reaction.
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References
Voit, C., Z. Biol., 2, 307 (1866).
Martin, C. J., and Robison, R., Biochem. J., 16, 407 (1922).
Campbell, R. M., and Kosterlitz, H. W., Biochem. J., 43, 416 (1948).
Holt, L. E., and Halac, E., J. Amer. Med. Assoc., 181, 699 (1962).
Allison, J. B., and Wannemacher, R. W., Amer. J. Clin. Nutrit., 16, 445 (1965).
Borsook, H., and Keighley, G. H., Proc. Roy. Soc., B, 118, 488 (1935).
Borsook, H., and Dubnoff, J. W., Ann. Rev. Biochem., 12, 183 (1943).
Comar, C. L., Radioisotopes in Biology and Agriculture, 18 (McGraw-Hill, New York, 1955).
Lusk, G., The Elements of the Science of Nutrition, fourth ed., 358 (W. B. Saunders Co., Philadelphia and London, 1928).
Bender, A. E., and Miller, D. S., Biochem. J., 53, vii (1953).
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YAMAGUCHI, M., KANDATSU, M. Catabolic Rate of Body Protein in Rat during the Earlier Stages of Protein Depletion. Nature 217, 668–669 (1968). https://doi.org/10.1038/217668b0
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DOI: https://doi.org/10.1038/217668b0
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