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Production of Foetal Haemoglobin in Marrow Cultures of Human Adults


IN the usual conditions of marrow culture, haemoglobin synthesis is maintained for only short periods. Kraus (ref. 1 and personal communication) reported on a long-term bone marrow culture method maintained at less than 37° C. In experimenting with this technique, we observed increased foetal (α2γ2) haemoglobin synthesis in culturing adult marrows.

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HALL, J., MOTULSKY, A. Production of Foetal Haemoglobin in Marrow Cultures of Human Adults. Nature 217, 569–571 (1968).

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