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Production of Foetal Haemoglobin in Marrow Cultures of Human Adults

Abstract

IN the usual conditions of marrow culture, haemoglobin synthesis is maintained for only short periods. Kraus (ref. 1 and personal communication) reported on a long-term bone marrow culture method maintained at less than 37° C. In experimenting with this technique, we observed increased foetal (α2γ2) haemoglobin synthesis in culturing adult marrows.

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References

  1. Kraus, L. M., Nature, 192, 1055 (1961).

    ADS  CAS  Article  Google Scholar 

  2. Huehns, E. R., and Shooter, E. M., J. Med. Genet., 2, 48 (1965).

    CAS  Article  Google Scholar 

  3. Betke, K., Marti, H. R., and Schlicht, I., Nature, 184, 1877 (1959).

    ADS  CAS  Article  Google Scholar 

  4. Bray, G. A., Anal. Biochem., 1, 279 (1960).

    CAS  Article  Google Scholar 

  5. Goldberg, I. H., and Rabinowitz, M., Science, 136, 315 (1962).

    ADS  CAS  Article  Google Scholar 

  6. Wilt, F. H., Amer. Zoologist, 6, 67 (1966).

    CAS  Article  Google Scholar 

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HALL, J., MOTULSKY, A. Production of Foetal Haemoglobin in Marrow Cultures of Human Adults. Nature 217, 569–571 (1968). https://doi.org/10.1038/217569a0

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