Abstract
IN the usual conditions of marrow culture, haemoglobin synthesis is maintained for only short periods. Kraus (ref. 1 and personal communication) reported on a long-term bone marrow culture method maintained at less than 37° C. In experimenting with this technique, we observed increased foetal (α2γ2) haemoglobin synthesis in culturing adult marrows.
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References
Kraus, L. M., Nature, 192, 1055 (1961).
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Goldberg, I. H., and Rabinowitz, M., Science, 136, 315 (1962).
Wilt, F. H., Amer. Zoologist, 6, 67 (1966).
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HALL, J., MOTULSKY, A. Production of Foetal Haemoglobin in Marrow Cultures of Human Adults. Nature 217, 569–571 (1968). https://doi.org/10.1038/217569a0
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DOI: https://doi.org/10.1038/217569a0
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